Leukemic RNA-pulsed DCs induce anti-AML cytotoxic activity in vitro.

2004 APR 13 - (NewsRx.com & NewsRx.net) -- Dendritic cells pulsed with leukemic RNA can induce antitumor cytotoxic activity in vitro.

According to recent research from South Korea, "[p]eptide-pulsed dendritic cells can stimulate T cells showing specific cytotoxicity in chronic myelogenous leukemia."

C.W. Jung and coauthors at Hanyang University Hospital "tried to induce a specific cytotoxic T-cell response stimulated by RNA-pulsed dendritic cells in acute myelogenous leukemia."

"The total RNA of WEHI-3BD+, a myelomonocytic leukemia cell line derived from BALB/c mice, was transfected into dendritic cells induced from bone marrow nucleated cells of …